Using and setting up the Apogee Electronics Duet 2 isn't difficult, as the software it comes with makes it easy to route and control everything inside the box. The digital interface on the actual device is easy to use as you can scroll through different screens to controls your preamp, headphone, and monitors levels. There's not too much to get acquainted with here as I think users will be able to get used to it rather quickly, although the manual might be a good idea for beginners.
The sound of the Apogee Electronics Duet 2 is quite stellar and is everything you would expect from Apogee. The conversion quality is top rate and the preamps sound pretty darn good to me although I haven't had a chance to shoot them out with other audio interfaces' preamps. The sound is by far the best thing about the Apogee as it gives you a pro's sound in a small box for a fraction of the price of other pro interfaces and converters.
The Apogee Electronics Duet 2 is the perfect audio interface for the home studio owner who is doing most of their work inside the box. For producers working primarily in Logic, you can't find a better deal. If you need more inputs and outputs and are using Pro Tools primarily, it may not be your best bet, but for those looking for something with great converters and a few nice preamps, the Duet 2 is a can't miss. The price is great considering what you're getting. The Duet 2 is very popular for good reasons!